Case Control Study Definition A study that compares patients who have a disease or outcome of interest (cases) with patients who do not have the disease or outcome (controls), and looks back retrospectively to compare how frequently the exposure to a risk factor is present in each group to determine the relationship between the risk …
A case-control study is designed to help determine if an exposure is associated with an outcome (i.e., disease or condition of interest). In theory, the case-control study can be described simply. First, identify the cases (a group known to have the outcome) and the controls (a group known to be
Observational studies are an important category of study designs. To address some investigative questions in plastic surgery, randomized controlled trials are not always indicated or ethical to conduct. Instead, observational studies may be the next best method to address these types of questions
“Case-control studies are best understood by considering as the starting point a source population, which represents a hypothetical study population in which a cohort study might have been conducted. The source population is the population that gives rise to the cases included in the study.
case-control study a nonexperimental research design using an epidemiological approach in which previous cases of the condition are used in lieu of new information gathered from a randomized population. A group of patients with a particular disease or disorder, such as myocardial infarction, is compared with a control group of persons …
Case-control study. Case–control studies are the most widely employed genetic association studies which compare two groups of subjects (a healthy control group versus a case group displaying the disease).
Case-control and cohort studies are observational studies that lie near the middle of the hierarchy of evidence. These types of studies, along with randomised controlled trials, constitute analytical studies, whereas case reports and case series define descriptive studies …
Case-control studies. As discussed in the previous chapter, one of the drawbacks of using a longitudinal approach to investigate the causes of disease with low incidence is that large and lengthy studies may be required to give adequate statistical power. An alternative which avoids this difficulty is the case-control or case-referent design.
by Annette Gerritsen, Ph.D. Two designs commonly used in epidemiology are the cohort and case-control studies. Both study causal relationships between a risk factor and a disease. What is the difference between these two designs? And when should you opt